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4fqg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the TCERG1 FF4-6 tandem repeat domain== | |
| - | + | <StructureSection load='4fqg' size='340' side='right'caption='[[4fqg]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4fqg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQG FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqg OCA], [https://pdbe.org/4fqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqg RCSB], [https://www.ebi.ac.uk/pdbsum/4fqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fan S]] | ||
| + | [[Category: Greenleaf AL]] | ||
| + | [[Category: Lee CJ]] | ||
| + | [[Category: Liu J]] | ||
| + | [[Category: Zhou P]] | ||
Current revision
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
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Categories: Homo sapiens | Large Structures | Fan S | Greenleaf AL | Lee CJ | Liu J | Zhou P
