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4gck
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| - | {{STRUCTURE_4gck| PDB=4gck | SCENE= }} | ||
| - | ===structure of no-dna complex=== | ||
| - | {{ABSTRACT_PUBMED_23754405}} | ||
| - | == | + | ==structure of no-dna complex== |
| - | [[http://www.uniprot.org/uniprot/SLMA_KLEP3 SLMA_KLEP3 | + | <StructureSection load='4gck' size='340' side='right'caption='[[4gck]], [[Resolution|resolution]] 2.05Å' scene=''> |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4gck]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gck OCA], [https://pdbe.org/4gck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gck RCSB], [https://www.ebi.ac.uk/pdbsum/4gck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gck ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| + | [https://www.uniprot.org/uniprot/SLMA_KLEP3 SLMA_KLEP3] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Klebsiella pneumoniae 342]] | [[Category: Klebsiella pneumoniae 342]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Schumacher MA]] |
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Current revision
structure of no-dna complex
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