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4gt8

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==Crystal Structure of the Catalytic and ATP-binding Domain from VraS in Complex with ADP==
==Crystal Structure of the Catalytic and ATP-binding Domain from VraS in Complex with ADP==
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<StructureSection load='4gt8' size='340' side='right' caption='[[4gt8]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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<StructureSection load='4gt8' size='340' side='right'caption='[[4gt8]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GT8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gt8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GT8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAV1885, vraS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gt8 OCA], [https://pdbe.org/4gt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gt8 RCSB], [https://www.ebi.ac.uk/pdbsum/4gt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gt8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gt8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gt8 RCSB], [http://www.ebi.ac.uk/pdbsum/4gt8 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VRAS_STAAM VRAS_STAAM] Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. Probably activates VraR by phosphorylation (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus mu50]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Leonard, P G]]
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[[Category: Leonard PG]]
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[[Category: Stock, A M]]
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[[Category: Stock AM]]
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[[Category: Valverde, J]]
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[[Category: Valverde J]]
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[[Category: Atp hydrolysis]]
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[[Category: Atp-binding]]
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[[Category: Bacterial signalling]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Phosphorylation]]
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[[Category: Transferase]]
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[[Category: Two-component system]]
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Current revision

Crystal Structure of the Catalytic and ATP-binding Domain from VraS in Complex with ADP

PDB ID 4gt8

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