4h61
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4h61 is ON HOLD Authors: Lariviere, L., Plaschka, C., Seizl, M., Wenzeck, L., Kurth, F., Cramer, P. Description: Structure of the Schizosaccharomyc...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the Schizosaccharomyces pombe Mediator subunit Med6== | |
| - | + | <StructureSection load='4h61' size='340' side='right'caption='[[4h61]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4h61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H61 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h61 OCA], [https://pdbe.org/4h61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h61 RCSB], [https://www.ebi.ac.uk/pdbsum/4h61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h61 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MED6_SCHPO MED6_SCHPO] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe 972h-]] | ||
| + | [[Category: Cramer P]] | ||
| + | [[Category: Kurth F]] | ||
| + | [[Category: Lariviere L]] | ||
| + | [[Category: Plaschka C]] | ||
| + | [[Category: Seizl M]] | ||
| + | [[Category: Wenzeck L]] | ||
Current revision
Structure of the Schizosaccharomyces pombe Mediator subunit Med6
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