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4hhv
From Proteopedia
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| - | {{STRUCTURE_4hhv| PDB=4hhv | SCENE= }} | ||
| - | ===Crystal structure of ceramide transfer protein pleckstrin homology domain=== | ||
| - | {{ABSTRACT_PUBMED_24260258}} | ||
| - | == | + | ==Crystal structure of ceramide transfer protein pleckstrin homology domain== |
| - | [[ | + | <StructureSection load='4hhv' size='340' side='right'caption='[[4hhv]], [[Resolution|resolution]] 1.75Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4hhv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HHV FirstGlance]. <br> |
| - | [[4hhv]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hhv OCA], [https://pdbe.org/4hhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hhv RCSB], [https://www.ebi.ac.uk/pdbsum/4hhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hhv ProSAT]</span></td></tr> |
| - | < | + | </table> |
| - | [[ | + | == Disease == |
| - | [[ | + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] The disease is caused by variants affecting the gene represented in this entry. |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CERT_HUMAN CERT_HUMAN] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Prashek J]] | ||
| + | [[Category: Truong T]] | ||
| + | [[Category: Yao X]] | ||
Current revision
Crystal structure of ceramide transfer protein pleckstrin homology domain
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