This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4hpw
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4hpw| PDB=4hpw | SCENE= }} | ||
| - | ===Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine=== | ||
| - | == | + | ==Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine== |
| - | [[http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA | + | <StructureSection load='4hpw' size='340' side='right'caption='[[4hpw]], [[Resolution|resolution]] 2.00Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4hpw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HPW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.998Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3YM:3-METHOXY-L-TYROSINE'>3YM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpw OCA], [https://pdbe.org/4hpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hpw RCSB], [https://www.ebi.ac.uk/pdbsum/4hpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SYY_METJA SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | <references | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Dong | + | [[Category: Methanocaldococcus jannaschii DSM 2661]] |
| - | [[Category: Gao | + | [[Category: Dong J]] |
| - | [[Category: Gong | + | [[Category: Gao F]] |
| - | [[Category: Li | + | [[Category: Gong W]] |
| - | [[Category: Li | + | [[Category: Li H]] |
| - | [[Category: Lu | + | [[Category: Li J]] |
| - | [[Category: Mukherjee | + | [[Category: Lu Y]] |
| - | [[Category: Nilges | + | [[Category: Mukherjee A]] |
| - | [[Category: Ouyang | + | [[Category: Nilges M]] |
| - | [[Category: Wang | + | [[Category: Ouyang H]] |
| - | [[Category: Xiaoxuan | + | [[Category: Wang J]] |
| - | [[Category: | + | [[Category: Xiaoxuan L]] |
| - | [[Category: Zhou | + | [[Category: Yu Y]] |
| - | + | [[Category: Zhou Q]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine
| |||||||||||
Categories: Large Structures | Methanocaldococcus jannaschii DSM 2661 | Dong J | Gao F | Gong W | Li H | Li J | Lu Y | Mukherjee A | Nilges M | Ouyang H | Wang J | Xiaoxuan L | Yu Y | Zhou Q
