This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4iqa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:58, 1 March 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure Analysis of the E228L Mutant of Human CLIC1==
==Crystal Structure Analysis of the E228L Mutant of Human CLIC1==
-
<StructureSection load='4iqa' size='340' side='right' caption='[[4iqa]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
+
<StructureSection load='4iqa' size='340' side='right'caption='[[4iqa]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4iqa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IQA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4iqa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IQA FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uvh|3uvh]], [[3p8w|3p8w]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLIC1, G6, NCC27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iqa OCA], [https://pdbe.org/4iqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iqa RCSB], [https://www.ebi.ac.uk/pdbsum/4iqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iqa ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iqa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iqa RCSB], [http://www.ebi.ac.uk/pdbsum/4iqa PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
+
[https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref>
 +
 
 +
==See Also==
 +
*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 14: Line 17:
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Achilonu, I A]]
+
[[Category: Large Structures]]
-
[[Category: Cross, M O]]
+
[[Category: Achilonu IA]]
-
[[Category: Dirr, H W]]
+
[[Category: Cross MO]]
-
[[Category: Fanucchi, S]]
+
[[Category: Dirr HW]]
-
[[Category: Fernandes, M A]]
+
[[Category: Fanucchi S]]
-
[[Category: Clic]]
+
[[Category: Fernandes MA]]
-
[[Category: Glutathione transferase]]
+
-
[[Category: Ph salt bridge ion channel]]
+
-
[[Category: Transport protein]]
+

Current revision

Crystal Structure Analysis of the E228L Mutant of Human CLIC1

PDB ID 4iqa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4iqa"
Personal tools