This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4j5h
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site== | |
| - | + | <StructureSection load='4j5h' size='340' side='right'caption='[[4j5h]], [[Resolution|resolution]] 1.45Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4j5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J5H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1K4:N-DECANOYL-L-HOMOSERINE'>1K4</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5h OCA], [https://pdbe.org/4j5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j5h RCSB], [https://www.ebi.ac.uk/pdbsum/4j5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AHLL_BACTU AHLL_BACTU] Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL.<ref>PMID:15895999</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus thuringiensis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fast W]] | ||
| + | [[Category: Lajoie A]] | ||
| + | [[Category: Liu CF]] | ||
| + | [[Category: Liu D]] | ||
| + | [[Category: Momb J]] | ||
| + | [[Category: Petsko GA]] | ||
| + | [[Category: Ringe D]] | ||
| + | [[Category: Thomas PW]] | ||
Current revision
Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site
| |||||||||||
Categories: Bacillus thuringiensis | Large Structures | Fast W | Lajoie A | Liu CF | Liu D | Momb J | Petsko GA | Ringe D | Thomas PW
