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4jf2
From Proteopedia
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<StructureSection load='4jf2' size='340' side='right'caption='[[4jf2]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='4jf2' size='340' side='right'caption='[[4jf2]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_rhamnosus Lacticaseibacillus rhamnosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JF2 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jf2 OCA], [https://pdbe.org/4jf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4jf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jf2 ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | PreQ1 riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ1 during the biosynthesis of the essential tRNA base queuosine. We report what is to our knowledge the first preQ1-II riboswitch structure at 2.3-A resolution, which uses a previously uncharacterized fold to achieve effector recognition at the confluence of a three-way helical junction flanking a pseudoknotted ribosome-binding site. The results account for translational control mediated by the preQ1-II riboswitch class and expand the known repertoire of ligand-binding modes used by regulatory RNAs. | ||
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| - | Structure of a class II preQ riboswitch reveals ligand recognition by a new fold.,Liberman JA, Salim M, Krucinska J, Wedekind JE Nat Chem Biol. 2013 Apr 14. doi: 10.1038/nchembio.1231. PMID:23584677<ref>PMID:23584677</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 4jf2" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Riboswitch 3D structures|Riboswitch 3D structures]] | *[[Riboswitch 3D structures|Riboswitch 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Lacticaseibacillus rhamnosus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Liberman | + | [[Category: Liberman JA]] |
| - | [[Category: Wedekind | + | [[Category: Wedekind JE]] |
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Current revision
Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold
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