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4jfi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione== | |
| + | <StructureSection load='4jfi' size='340' side='right'caption='[[4jfi]], [[Resolution|resolution]] 1.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4jfi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JFI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1KT:1-[(9S,13R,13AR)-1,3-DIMETHOXY-8-OXO-5,8,9,10,11,12,13,13A-OCTAHYDRO-6H-9,13-EPIMINOAZOCINO[2,1-A]ISOQUINOLIN-14-YL]-2-(3,4,5-TRIMETHOXYPHENYL)ETHANE-1,2-DIONE'>1KT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jfi OCA], [https://pdbe.org/4jfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jfi RCSB], [https://www.ebi.ac.uk/pdbsum/4jfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jfi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP. | ||
| - | + | ==See Also== | |
| - | + | *[[FKBP 3D structures|FKBP 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bracher A]] | ||
| + | [[Category: Fabian A]] | ||
| + | [[Category: Gopalakrishnan R]] | ||
| + | [[Category: Hausch F]] | ||
| + | [[Category: Hoogeland B]] | ||
| + | [[Category: Kirschner A]] | ||
| + | [[Category: Koch U]] | ||
| + | [[Category: Kozany C]] | ||
| + | [[Category: Kress C]] | ||
| + | [[Category: Wang Y]] | ||
Current revision
Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione
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Categories: Homo sapiens | Large Structures | Bracher A | Fabian A | Gopalakrishnan R | Hausch F | Hoogeland B | Kirschner A | Koch U | Kozany C | Kress C | Wang Y
