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4jir
From Proteopedia
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| - | {{STRUCTURE_4jir| PDB=4jir | SCENE= }} | ||
| - | ===Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat=== | ||
| - | {{ABSTRACT_PUBMED_24100137}} | ||
| - | == | + | ==Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat== |
| - | [[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN | + | <StructureSection load='4jir' size='340' side='right'caption='[[4jir]], [[Resolution|resolution]] 2.00Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4jir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JIR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPR:{5-[(2E)-2-METHYL-3-PHENYLPROP-2-EN-1-YLIDENE]-4-OXO-2-THIOXO-1,3-THIAZOLIDIN-3-YL}ACETIC+ACID'>EPR</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jir OCA], [https://pdbe.org/4jir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jir RCSB], [https://www.ebi.ac.uk/pdbsum/4jir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jir ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Aldose reductase 3D structures|Aldose reductase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Homo sapiens]] | |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chen K]] |
| - | [[Category: Chen | + | [[Category: Hu X]] |
| - | [[Category: Hu | + | [[Category: Zhai J]] |
| - | [[Category: Zhai | + | [[Category: Zhang H]] |
| - | [[Category: Zhang | + | [[Category: Zhang L]] |
| - | [[Category: Zhang | + | [[Category: Zhao Y]] |
| - | [[Category: Zhao | + | [[Category: Zheng X]] |
| - | [[Category: Zheng | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat
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Categories: Homo sapiens | Large Structures | Chen K | Hu X | Zhai J | Zhang H | Zhang L | Zhao Y | Zheng X
