4k1c
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4k1c is ON HOLD Authors: Waight, A.B., Pedersen, B.P., Stroud, R.M., Center for Structures of Membrane Proteins (CSMP) Description: VCX1 Calcium/Pr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==VCX1 Calcium/Proton Exchanger== | |
| - | + | <StructureSection load='4k1c' size='340' side='right'caption='[[4k1c]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4k1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1c OCA], [https://pdbe.org/4k1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1c RCSB], [https://www.ebi.ac.uk/pdbsum/4k1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1c ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VCX1_YEAST VCX1_YEAST] Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.<ref>PMID:8668190</ref> <ref>PMID:8628289</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Pedersen BP]] | ||
| + | [[Category: Stroud RM]] | ||
| + | [[Category: Waight AB]] | ||
Current revision
VCX1 Calcium/Proton Exchanger
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