4k7q
From Proteopedia
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| - | {{STRUCTURE_4k7q| PDB=4k7q | SCENE= }} | ||
| - | ===Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution=== | ||
| - | {{ABSTRACT_PUBMED_23673416}} | ||
| - | == | + | ==Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution== |
| - | [[ | + | <StructureSection load='4k7q' size='340' side='right'caption='[[4k7q]], [[Resolution|resolution]] 3.50Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4k7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7Q FirstGlance]. <br> |
| - | [[4k7q]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZLD:N-{[(5S)-3-(3-FLUORO-4-MORPHOLIN-4-YLPHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL]METHYL}ACETAMIDE'>ZLD</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7q OCA], [https://pdbe.org/4k7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7q RCSB], [https://www.ebi.ac.uk/pdbsum/4k7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7q ProSAT]</span></td></tr> |
| - | < | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Gupta G]] |
| + | [[Category: Hung LW]] | ||
| + | [[Category: Kim CY]] | ||
| + | [[Category: Kim HB]] | ||
| + | [[Category: Murakami S]] | ||
| + | [[Category: Terwilliger TC]] | ||
Current revision
Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution
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