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4kvo

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{{STRUCTURE_4kvo| PDB=4kvo | SCENE= }}
 
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===The NatA (Naa10p/Naa15p) amino-terminal acetyltrasferase complex bound to AcCoA===
 
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==Function==
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==The NatA (Naa10p/Naa15p) amino-terminal acetyltrasferase complex bound to AcCoA==
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[[http://www.uniprot.org/uniprot/NAT1_SCHPO NAT1_SCHPO]] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. nat1 anchors ard1 and nat5 to the ribosome and may present the N termini of nascent polypeptides for acetylation (By similarity). [[http://www.uniprot.org/uniprot/ARD1_SCHPO ARD1_SCHPO]] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover (By similarity).
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<StructureSection load='4kvo' size='340' side='right'caption='[[4kvo]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4kvo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KVO FirstGlance]. <br>
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[[4kvo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVO OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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[[Category: Peptide alpha-N-acetyltransferase]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kvo OCA], [https://pdbe.org/4kvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kvo RCSB], [https://www.ebi.ac.uk/pdbsum/4kvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kvo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAT1_SCHPO NAT1_SCHPO] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. nat1 anchors ard1 and nat5 to the ribosome and may present the N termini of nascent polypeptides for acetylation (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Liszczak, G P.]]
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[[Category: Liszczak GP]]
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[[Category: Marmorstein, R Q.]]
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[[Category: Marmorstein RQ]]
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[[Category: Acetyltransferase]]
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[[Category: Amino-terminal acetyltransferase]]
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[[Category: Transferase]]
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Current revision

The NatA (Naa10p/Naa15p) amino-terminal acetyltrasferase complex bound to AcCoA

PDB ID 4kvo

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