4l6h
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4l6h is ON HOLD Authors: Ubhi, D, Robertus, J. D Description: Crystal structure of the Candida albicans Methionine Synthase in complex with Methotr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine== | |
| + | <StructureSection load='4l6h' size='340' side='right'caption='[[4l6h]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4l6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L6H FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=MTX:METHOTREXATE'>MTX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6h OCA], [https://pdbe.org/4l6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l6h RCSB], [https://www.ebi.ac.uk/pdbsum/4l6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/METE_CANAL METE_CANAL] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.[HAMAP-Rule:MF_00172] | ||
| - | + | ==See Also== | |
| - | + | *[[Methionine synthase 3D structures|Methionine synthase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Candida albicans SC5314]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Robertus JD]] | ||
| + | [[Category: Ubhi D]] | ||
Current revision
Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine
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