4lkt

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{{STRUCTURE_4lkt| PDB=4lkt | SCENE= }}
 
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===Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid===
 
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==Function==
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==Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid==
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[[http://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN]] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
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<StructureSection load='4lkt' size='340' side='right'caption='[[4lkt]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lkt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LKT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EIC:LINOLEIC+ACID'>EIC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lkt OCA], [https://pdbe.org/4lkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lkt RCSB], [https://www.ebi.ac.uk/pdbsum/4lkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lkt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.
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==About this Structure==
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==See Also==
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[[4lkt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LKT OCA].
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*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
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[[Category: Armstrong, E H.]]
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__TOC__
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[[Category: Ortlund, E A.]]
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</StructureSection>
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[[Category: Beta barrel]]
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[[Category: Homo sapiens]]
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[[Category: Beta clam]]
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[[Category: Large Structures]]
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[[Category: Fatty acid binding protein]]
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[[Category: Armstrong EH]]
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[[Category: Fatty acid]]
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[[Category: Ortlund EA]]
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[[Category: Lipid binding protein]]
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[[Category: Nucleus]]
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Current revision

Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid

PDB ID 4lkt

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