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4mb8

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{{STRUCTURE_4mb8| PDB=4mb8 | SCENE= }}
 
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===Evolutionary history and metabolic insights of ancient mammalian uricases===
 
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{{ABSTRACT_PUBMED_24550457}}
 
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==Function==
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==Evolutionary history and metabolic insights of ancient mammalian uricases==
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[[http://www.uniprot.org/uniprot/URIC_CANFA URIC_CANFA]] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
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<StructureSection load='4mb8' size='340' side='right'caption='[[4mb8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4mb8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Unclassified_Mammalia Unclassified Mammalia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MB8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4009&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mb8 OCA], [https://pdbe.org/4mb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mb8 RCSB], [https://www.ebi.ac.uk/pdbsum/4mb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mb8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/URIC_CANLF URIC_CANLF] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
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==About this Structure==
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==See Also==
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[[4mb8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA].
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*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024550457</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Factor independent urate hydroxylase]]
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[[Category: Unclassified Mammalia]]
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[[Category: Murphy, M N.]]
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[[Category: Murphy MN]]
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[[Category: Ortlund, E O.]]
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[[Category: Ortlund EO]]
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[[Category: Lysozome]]
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[[Category: Oxidoreductase]]
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[[Category: Uric acid oxidase]]
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Current revision

Evolutionary history and metabolic insights of ancient mammalian uricases

PDB ID 4mb8

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