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4nlh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==SKICH domain of human TAX1BP1== | |
| - | + | <StructureSection load='4nlh' size='340' side='right'caption='[[4nlh]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4nlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NLH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nlh OCA], [https://pdbe.org/4nlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nlh RCSB], [https://www.ebi.ac.uk/pdbsum/4nlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nlh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TAXB1_HUMAN TAXB1_HUMAN] Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.<ref>PMID:10435631</ref> <ref>PMID:10920205</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Du Z]] | ||
| + | [[Category: Huang X]] | ||
| + | [[Category: Wang G]] | ||
| + | [[Category: Yang Y]] | ||
| + | [[Category: Zhu J]] | ||
Current revision
SKICH domain of human TAX1BP1
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Categories: Homo sapiens | Large Structures | Du Z | Huang X | Wang G | Yang Y | Zhu J
