This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4nn2
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6== | ==Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6== | ||
| - | <StructureSection load='4nn2' size='340' side='right' caption='[[4nn2]], [[Resolution|resolution]] 1.47Å' scene=''> | + | <StructureSection load='4nn2' size='340' side='right'caption='[[4nn2]], [[Resolution|resolution]] 1.47Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nn2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nn2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NN2 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.472Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nn2 OCA], [https://pdbe.org/4nn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nn2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nn2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Li | + | [[Category: Large Structures]] |
| - | [[Category: Liu | + | [[Category: Li F]] |
| - | [[Category: Mei | + | [[Category: Liu Z]] |
| - | [[Category: Shi | + | [[Category: Mei Y]] |
| - | [[Category: Wu | + | [[Category: Shi Y]] |
| - | [[Category: Zhang | + | [[Category: Wu J]] |
| - | + | [[Category: Zhang J]] | |
| - | + | ||
Current revision
Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6
| |||||||||||
Categories: Homo sapiens | Large Structures | Li F | Liu Z | Mei Y | Shi Y | Wu J | Zhang J
