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4rvj

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==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with amprenavir==
==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with amprenavir==
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<StructureSection load='4rvj' size='340' side='right' caption='[[4rvj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4rvj' size='340' side='right'caption='[[4rvj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rvj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rvj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=478:{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC+ACID+TETRAHYDRO-FURAN-3-YL+ESTER'>478</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4njs|4njs]], [[4njt|4njt]], [[4nju|4nju]], [[4njv|4njv]], [[4hla|4hla]], [[4rvi|4rvi]], [[4rvv|4rvv]], [[4rvx|4rvx]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=478:{3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC+ACID+TETRAHYDRO-FURAN-3-YL+ESTER'>478</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvj OCA], [http://pdbe.org/4rvj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvj RCSB], [http://www.ebi.ac.uk/pdbsum/4rvj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvj OCA], [https://pdbe.org/4rvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvj RCSB], [https://www.ebi.ac.uk/pdbsum/4rvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvj ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9J006_9HIV1 Q9J006_9HIV1]
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==See Also==
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Das, D]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Garimella, H]]
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[[Category: Large Structures]]
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[[Category: Kaufman, J D]]
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[[Category: Das D]]
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[[Category: Mitsuya, H]]
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[[Category: Garimella H]]
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[[Category: Wingfield, P T]]
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[[Category: Kaufman JD]]
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[[Category: Yedidi, R S]]
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[[Category: Mitsuya H]]
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[[Category: Amprenavir]]
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[[Category: Wingfield PT]]
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[[Category: Hiv-1 protease-inhibitor complex]]
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[[Category: Yedidi RS]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Non-peptidic protease inhibitor]]
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Current revision

Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with amprenavir

PDB ID 4rvj

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