4y95
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4y95 is ON HOLD Authors: Wang, Q., Rosen, C.E., Kuriyan, J. Description: Category: Unreleased Structures Category: Kuriyan, J [[Category: ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the kinase domain of Bruton's tyrosine kinase with mutations in the activation loop== | |
| + | <StructureSection load='4y95' size='340' side='right'caption='[[4y95]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4y95]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y95 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.599Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y95 OCA], [https://pdbe.org/4y95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y95 RCSB], [https://www.ebi.ac.uk/pdbsum/4y95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y95 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q3ZC95_BOVIN Q3ZC95_BOVIN] | ||
| - | + | ==See Also== | |
| - | + | *[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Kuriyan | + | [[Category: Bos taurus]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Kuriyan J]] |
| + | [[Category: Rosen CE]] | ||
| + | [[Category: Wang Q]] | ||
Current revision
Crystal structure of the kinase domain of Bruton's tyrosine kinase with mutations in the activation loop
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