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3phw
From Proteopedia
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| - | [[Image:3phw.png|left|200px]] | ||
| - | + | ==OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin== | |
| - | + | <StructureSection load='3phw' size='340' side='right'caption='[[3phw]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3phw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Crimean-Congo_hemorrhagic_fever_virus_strain_IbAr10200 Crimean-Congo hemorrhagic fever virus strain IbAr10200] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEH:ETHANAMINE'>NEH</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phw OCA], [https://pdbe.org/3phw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phw RCSB], [https://www.ebi.ac.uk/pdbsum/3phw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phw ProSAT]</span></td></tr> |
| - | [[3phw]] is a 8 chain structure with sequence from [ | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity. | ||
==See Also== | ==See Also== | ||
| - | *[[RNA polymerase|RNA polymerase]] | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Crimean-Congo hemorrhagic fever virus strain IbAr10200]] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Akutsu | + | [[Category: Akutsu M]] |
| - | [[Category: Komander | + | [[Category: Komander D]] |
| - | [[Category: Virdee | + | [[Category: Virdee S]] |
| - | [[Category: Ye | + | [[Category: Ye Y]] |
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Current revision
OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin
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