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3pjs
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| - | [[Image:3pjs.png|left|200px]] | ||
| - | + | ==Mechanism of Activation Gating in the Full-Length KcsA K+ Channel== | |
| - | + | <StructureSection load='3pjs' size='340' side='right'caption='[[3pjs]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3pjs]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjs OCA], [https://pdbe.org/3pjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pjs RCSB], [https://www.ebi.ac.uk/pdbsum/3pjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pjs ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[3pjs]] is a 8 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/KCSA_STRLI KCSA_STRLI] Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening. Monovalent cation preference is K(+) > Rb(+) > NH4(+) >> Na(+) > Li(+).<ref>PMID:7489706</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Antibody|Antibody]] | + | *[[Antibody 3D structures|Antibody 3D structures]] |
| - | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | |
| - | == | + | *[[3D structures of non-human antibody|3D structures of non-human antibody]] |
| - | < | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Streptomyces lividans]] | [[Category: Streptomyces lividans]] | ||
| - | [[Category: Cuello | + | [[Category: Cuello LG]] |
| - | [[Category: Kossiakoff | + | [[Category: Kossiakoff A]] |
| - | [[Category: Perozo | + | [[Category: Perozo E]] |
| - | [[Category: Uysal | + | [[Category: Uysal S]] |
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Current revision
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
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