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3pmb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3pmb is ON HOLD Authors: Wright, H.T., Scarsdale, J.N., Desai, B.J. Description: 2.9 Angstrom crystal structure of bovine thrombin in tetragonal sp...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==2.9 Angstrom crystal structure of bovine thrombin in tetragonal spacegroup== | |
| + | <StructureSection load='3pmb' size='340' side='right'caption='[[3pmb]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pmb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmb OCA], [https://pdbe.org/3pmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pmb RCSB], [https://www.ebi.ac.uk/pdbsum/3pmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pmb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Thrombin 3D Structures|Thrombin 3D Structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Bos taurus]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Desai BJ]] | ||
| + | [[Category: Scarsdale JN]] | ||
| + | [[Category: Wright HT]] | ||
Current revision
2.9 Angstrom crystal structure of bovine thrombin in tetragonal spacegroup
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