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3pmi

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(New page: '''Unreleased structure''' The entry 3pmi is ON HOLD Authors: Lam, R., Zeng, H., Loppnau, P., Bountra, C., Weigelt, J., Arrowsmith, C. H., Edwards, A. M., Bochkarev, A., Min, J., Wu, H....)
Current revision (13:32, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3pmi is ON HOLD
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==PWWP Domain of Human Mutated Melanoma-Associated Antigen 1==
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<StructureSection load='3pmi' size='340' side='right'caption='[[3pmi]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
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Authors: Lam, R., Zeng, H., Loppnau, P., Bountra, C., Weigelt, J., Arrowsmith, C. H., Edwards, A. M., Bochkarev, A., Min, J., Wu, H., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3pmi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PMI FirstGlance]. <br>
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Description: PWWP Domain of Human Mutated Melanoma-Associated Antigen 1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 13:58:58 2010''
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pmi OCA], [https://pdbe.org/3pmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pmi RCSB], [https://www.ebi.ac.uk/pdbsum/3pmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pmi ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PWP3A_HUMAN PWP3A_HUMAN] Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.<ref>PMID:20347427</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev A]]
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[[Category: Bountra C]]
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[[Category: Edwards AM]]
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[[Category: Lam R]]
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[[Category: Loppnau P]]
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[[Category: Min J]]
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[[Category: Weigelt J]]
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[[Category: Wu H]]
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[[Category: Zeng H]]

Current revision

PWWP Domain of Human Mutated Melanoma-Associated Antigen 1

PDB ID 3pmi

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