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3pzd
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3pzd is ON HOLD Authors: Wei, Z., Yan, J., Pan, L., Zhang, M. Description: Structure of the myosin X MyTH4-FERM/DCC complex ''Page seeded by [http...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the myosin X MyTH4-FERM/DCC complex== | |
| + | <StructureSection load='3pzd' size='340' side='right'caption='[[3pzd]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3pzd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pzd OCA], [https://pdbe.org/3pzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pzd RCSB], [https://www.ebi.ac.uk/pdbsum/3pzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pzd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYO10_HUMAN MYO10_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).<ref>PMID:16894163</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Myosin 3D Structures|Myosin 3D Structures]] | |
| - | + | *[[Netrin receptor|Netrin receptor]] | |
| - | + | == References == | |
| - | + | <references/> | |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Pan L]] | ||
| + | [[Category: Wei Z]] | ||
| + | [[Category: Yan J]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Structure of the myosin X MyTH4-FERM/DCC complex
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Categories: Homo sapiens | Large Structures | Mus musculus | Pan L | Wei Z | Yan J | Zhang M
