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3q0i

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==Methionyl-tRNA formyltransferase from Vibrio cholerae==
==Methionyl-tRNA formyltransferase from Vibrio cholerae==
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<StructureSection load='3q0i' size='340' side='right' caption='[[3q0i]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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<StructureSection load='3q0i' size='340' side='right'caption='[[3q0i]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3q0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q0I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3q0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fmt, VC_0045 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0i OCA], [https://pdbe.org/3q0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0i RCSB], [https://www.ebi.ac.uk/pdbsum/3q0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0i ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl-tRNA_formyltransferase Methionyl-tRNA formyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.9 2.1.2.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0i OCA], [http://pdbe.org/3q0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q0i RCSB], [http://www.ebi.ac.uk/pdbsum/3q0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0i ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FMT_VIBCH FMT_VIBCH]] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).
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[https://www.uniprot.org/uniprot/FMT_VIBCH FMT_VIBCH] Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillo virgola del koch trevisan 1884]]
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[[Category: Large Structures]]
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[[Category: Methionyl-tRNA formyltransferase]]
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[[Category: Vibrio cholerae]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Gu M]]
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[[Category: Gu, M]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J]]
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[[Category: Papazisi L]]
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[[Category: Papazisi, L]]
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[[Category: Csgid]]
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[[Category: Transferase]]
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Current revision

Methionyl-tRNA formyltransferase from Vibrio cholerae

PDB ID 3q0i

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