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4hpd
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4hpd is ON HOLD Authors: Nishikawa, K., Ogata, H., Knipp, M. Description: Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with homocysteine at pH 7.4== | |
| + | <StructureSection load='4hpd' size='340' side='right'caption='[[4hpd]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4hpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HPD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpd OCA], [https://pdbe.org/4hpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hpd RCSB], [https://www.ebi.ac.uk/pdbsum/4hpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Nitrophorin|Nitrophorin]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rhodnius prolixus]] | ||
| + | [[Category: Knipp M]] | ||
| + | [[Category: Nishikawa K]] | ||
| + | [[Category: Ogata H]] | ||
Current revision
Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with homocysteine at pH 7.4
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