4zra

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'''Unreleased structure'''
 
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The entry 4zra is ON HOLD until Paper Publication
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==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE==
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<StructureSection load='4zra' size='340' side='right'caption='[[4zra]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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Authors: Martinot, A.J., Farrow, M., Bai, L., Layre, E., Cheng, T.Y., Tsai, J.H.C., Iqbal, J., Annand, J., Sullivan, Z., Hussain, M., Sacchettini, J., Moody, D.B., Seeliger, J., Rubin, E.J., TB Structural Genomics Consortium (TBSGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4zra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZRA FirstGlance]. <br>
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Description: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4RF:TRIPALMITOYLGLYCEROL'>4RF</scene></td></tr>
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[[Category: Hussain, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zra OCA], [https://pdbe.org/4zra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zra RCSB], [https://www.ebi.ac.uk/pdbsum/4zra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zra ProSAT]</span></td></tr>
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[[Category: Tsai, J.H.C]]
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</table>
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[[Category: Moody, D.B]]
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== Function ==
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[[Category: Layre, E]]
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[https://www.uniprot.org/uniprot/LPRG_MYCTU LPRG_MYCTU] TLR2 agonist that can inhibit primary human macrophage MHC-II Ag processing. Required for Rv1410c (P55) activity.<ref>PMID:15294983</ref> <ref>PMID:18156250</ref>
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[[Category: Bai, L]]
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== References ==
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[[Category: Farrow, M]]
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<references/>
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[[Category: Rubin, E.J]]
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__TOC__
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[[Category: Annand, J]]
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</StructureSection>
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[[Category: Cheng, T.Y]]
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[[Category: Large Structures]]
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[[Category: Sullivan, Z]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Seeliger, J]]
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[[Category: Annand J]]
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[[Category: Iqbal, J]]
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[[Category: Bai L]]
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[[Category: Martinot, A.J]]
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[[Category: Cheng TY]]
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[[Category: Sacchettini, J]]
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[[Category: Farrow M]]
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[[Category: Tb Structural Genomics Consortium (Tbsgc)]]
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[[Category: Hussain M]]
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[[Category: Iqbal J]]
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[[Category: Layre E]]
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[[Category: Martinot AJ]]
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[[Category: Moody DB]]
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[[Category: Rubin EJ]]
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[[Category: Sacchettini J]]
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[[Category: Seeliger J]]
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[[Category: Sullivan Z]]
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[[Category: Tsai JHC]]

Current revision

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE

PDB ID 4zra

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