This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5c1l
From Proteopedia
(Difference between revisions)
m (Protected "5c1l" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of GTB + UDP-Gal + DI== | |
| + | <StructureSection load='5c1l' size='340' side='right'caption='[[5c1l]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5c1l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C1L FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DA8:OCTYL+3-DEOXY-2-O-(6-DEOXY-ALPHA-L-GALACTOPYRANOSYL)-BETA-D-XYLO-HEXOPYRANOSIDE'>DA8</scene>, <scene name='pdbligand=GDU:GALACTOSE-URIDINE-5-DIPHOSPHATE'>GDU</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c1l OCA], [https://pdbe.org/5c1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c1l RCSB], [https://www.ebi.ac.uk/pdbsum/5c1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c1l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Borisova S]] |
| - | [[Category: | + | [[Category: Evans SV]] |
| - | [[Category: | + | [[Category: Gagnon S]] |
| - | [[Category: | + | [[Category: Haji-Ghassemi O]] |
| - | [[Category: | + | [[Category: Johal AR]] |
| - | [[Category: | + | [[Category: Lowary TL]] |
| + | [[Category: Meloncelli P]] | ||
| + | [[Category: Zheng RB]] | ||
Current revision
Crystal structure of GTB + UDP-Gal + DI
| |||||||||||
Categories: Homo sapiens | Large Structures | Borisova S | Evans SV | Gagnon S | Haji-Ghassemi O | Johal AR | Lowary TL | Meloncelli P | Zheng RB
