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5elh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5elh is ON HOLD until Paper Publication Authors: Teplova, M., Murn, J., Zarnack, K., Shi, Y., Patel, D.S. Description: Crystal structure of mouse U...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA== | |
| - | + | <StructureSection load='5elh' size='340' side='right'caption='[[5elh]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5elh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ELH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ELH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5elh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5elh OCA], [https://pdbe.org/5elh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5elh RCSB], [https://www.ebi.ac.uk/pdbsum/5elh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5elh ProSAT]</span></td></tr> |
| - | [[Category: Patel | + | </table> |
| - | [[Category: Shi | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/UNK_MOUSE UNK_MOUSE] Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).<ref>PMID:25737280</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Murn J]] | ||
| + | [[Category: Patel DJ]] | ||
| + | [[Category: Shi Y]] | ||
| + | [[Category: Teplova M]] | ||
| + | [[Category: Zarnack K]] | ||
Current revision
Crystal structure of mouse Unkempt zinc fingers 1-3 (ZnF1-3), bound to RNA
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Categories: Large Structures | Mus musculus | Murn J | Patel DJ | Shi Y | Teplova M | Zarnack K
