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5eqr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with danoprevir== | |
| + | <StructureSection load='5eqr' size='340' side='right'caption='[[5eqr]], [[Resolution|resolution]] 1.96Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5eqr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSV:(2R,6S,12Z,13AS,14AR,16AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-14A-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-5,16-DIOXO-1,2,3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-HEXADECAHYDROCYCLOPROPA[E]PYRROLO[1,2-A][1,4]DIAZACYCLOPENTADECIN-2-YL+4-FLUORO-2H-ISOINDOLE-2-CARBOXYLATE'>TSV</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqr OCA], [https://pdbe.org/5eqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqr RCSB], [https://www.ebi.ac.uk/pdbsum/5eqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0B4WYC6_9HEPC A0A0B4WYC6_9HEPC] | ||
| - | + | ==See Also== | |
| - | + | *[[Virus protease 3D structures|Virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Hepacivirus C]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ali A]] |
| - | [[Category: | + | [[Category: Prachanronarong KL]] |
| - | [[Category: | + | [[Category: Schiffer CA]] |
| + | [[Category: Soumana D]] | ||
| + | [[Category: Yilmaz NK]] | ||
Current revision
Crystal structure of a genotype 1a/3a chimeric HCV NS3/4A protease in complex with danoprevir
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