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5exi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution== | |
| - | + | <StructureSection load='5exi' size='340' side='right'caption='[[5exi]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5exi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EXI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5exi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5exi OCA], [https://pdbe.org/5exi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5exi RCSB], [https://www.ebi.ac.uk/pdbsum/5exi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5exi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIPA_MYCTU LIPA_MYCTU] Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Booker SJ]] | ||
| + | [[Category: Drennan CL]] | ||
| + | [[Category: Goldman PJ]] | ||
| + | [[Category: Lanz ND]] | ||
| + | [[Category: Lee K-H]] | ||
| + | [[Category: McLaughlin MI]] | ||
Current revision
Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution
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