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5rw1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition of ground-state model of DHTKD1== | |
| - | + | <StructureSection load='5rw1' size='340' side='right'caption='[[5rw1]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5rw1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5RW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5RW1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5rw1 OCA], [https://pdbe.org/5rw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5rw1 RCSB], [https://www.ebi.ac.uk/pdbsum/5rw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5rw1 ProSAT]</span></td></tr> |
| - | [[Category: Bailey | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] 2-aminoadipic 2-oxoadipic aciduria;Autosomal dominant Charcot-Marie-Tooth disease type 2Q. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
| - | [[Category: Brandao-Neto | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Edwards | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Krojer | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bailey HJ]] |
| - | [[Category: | + | [[Category: Bezerra GA]] |
| + | [[Category: Bountra C]] | ||
| + | [[Category: Brandao-Neto J]] | ||
| + | [[Category: Burgess-Brown N]] | ||
| + | [[Category: Douangamath A]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Foster WR]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Shrestha L]] | ||
| + | [[Category: Yue WW]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition of ground-state model of DHTKD1
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bailey HJ | Bezerra GA | Bountra C | Brandao-Neto J | Burgess-Brown N | Douangamath A | Edwards A | Foster WR | Krojer T | Shrestha L | Yue WW | Von Delft F
