This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5syb
From Proteopedia
(Difference between revisions)
(New page: ==Crystal structure of human PHF5A== <StructureSection load='5syb' size='340' side='right' caption='5syb, resolution 1.82Å' scene=''> == Structural highlights == ...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of human PHF5A== | ==Crystal structure of human PHF5A== | ||
| - | <StructureSection load='5syb' size='340' side='right' caption='[[5syb]], [[Resolution|resolution]] 1.82Å' scene=''> | + | <StructureSection load='5syb' size='340' side='right'caption='[[5syb]], [[Resolution|resolution]] 1.82Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5syb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYB OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5syb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYB FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5syb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5syb OCA], [https://pdbe.org/5syb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5syb RCSB], [https://www.ebi.ac.uk/pdbsum/5syb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5syb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PHF5A_HUMAN PHF5A_HUMAN] Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha. Also involved in pre-mRNA splicing.<ref>PMID:12234937</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fekkes P]] |
| - | + | [[Category: Larsen NA]] | |
| - | + | [[Category: Teng T]] | |
| - | [[Category: | + | [[Category: Tsai JHC]] |
| - | [[Category: | + | [[Category: Zhu P]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
Crystal structure of human PHF5A
| |||||||||||
Categories: Homo sapiens | Large Structures | Fekkes P | Larsen NA | Teng T | Tsai JHC | Zhu P
