5ujm

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m (Protected "5ujm" [edit=sysop:move=sysop])
Current revision (14:27, 6 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5ujm is ON HOLD
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==Structure of the active form of human Origin Recognition Complex and its ATPase motor module==
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<SX load='5ujm' size='340' side='right' viewer='molstar' caption='[[5ujm]], [[Resolution|resolution]] 18.00&Aring;' scene=''>
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Authors: Tocilj, A., On, K., Yuan, Z., Sun, J., Elkayam, E., Li, H., Stillman, B., Joshua-Tor, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ujm]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5UJM FirstGlance]. <br>
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Description: Structure of the active form of human Origin Recognition Complex and its ATPase motor module
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Joshua-Tor, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ujm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ujm OCA], [https://pdbe.org/5ujm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ujm RCSB], [https://www.ebi.ac.uk/pdbsum/5ujm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ujm ProSAT]</span></td></tr>
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[[Category: On, K]]
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</table>
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[[Category: Stillman, B]]
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== Disease ==
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[[Category: Li, H]]
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[https://www.uniprot.org/uniprot/ORC1_HUMAN ORC1_HUMAN] Ear-patella-short stature syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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[[Category: Elkayam, E]]
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== Function ==
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[[Category: Sun, J]]
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[https://www.uniprot.org/uniprot/ORC1_HUMAN ORC1_HUMAN] Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
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[[Category: Tocilj, A]]
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__TOC__
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[[Category: Yuan, Z]]
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</SX>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Elkayam E]]
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[[Category: Joshua-Tor L]]
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[[Category: Li H]]
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[[Category: On K]]
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[[Category: Stillman B]]
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[[Category: Sun J]]
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[[Category: Tocilj A]]
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[[Category: Yuan Z]]

Current revision

Structure of the active form of human Origin Recognition Complex and its ATPase motor module

5ujm, resolution 18.00Å

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OCA

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