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6is0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6is0 is ON HOLD Authors: Hirano, S., Nishimasu, H., Ishitani, R., Nureki, O. Description: Crystal structure of the zebrafish cap-specific adenosine...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA== | |
| - | + | <StructureSection load='6is0' size='340' side='right'caption='[[6is0]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6is0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IS0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5-DIPHOSPHATE'>M7G</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6is0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6is0 OCA], [https://pdbe.org/6is0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6is0 RCSB], [https://www.ebi.ac.uk/pdbsum/6is0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6is0 ProSAT]</span></td></tr> |
| - | [[Category: Hirano | + | </table> |
| - | [[Category: Nishimasu | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CAPAM_DANRE CAPAM_DANRE] Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs (PubMed:30467178).<ref>PMID:30467178</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Danio rerio]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Hirano S]] | ||
| + | [[Category: Ishitani R]] | ||
| + | [[Category: Nishimasu H]] | ||
| + | [[Category: Nureki O]] | ||
Current revision
Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
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