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6vp9
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6vp9 is ON HOLD Authors: Deng, S., Marmorstein, R. Description: Cryo-EM structure of human NatB complex Category: Unreleased Structures [[Categ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human NatB complex== | |
| - | + | <StructureSection load='6vp9' size='340' side='right'caption='[[6vp9]], [[Resolution|resolution]] 3.46Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6vp9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VP9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.46Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene></td></tr> |
| - | [[Category: Deng | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vp9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vp9 OCA], [https://pdbe.org/6vp9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vp9 RCSB], [https://www.ebi.ac.uk/pdbsum/6vp9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vp9 ProSAT]</span></td></tr> |
| - | [[Category: Marmorstein | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/NAA20_HUMAN NAA20_HUMAN] Autosomal recessive non-syndromic intellectual disability. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NAA20_HUMAN NAA20_HUMAN] Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln (PubMed:34230638). Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.<ref>PMID:18570629</ref> <ref>PMID:34230638</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng S]] | ||
| + | [[Category: Marmorstein R]] | ||
Current revision
Cryo-EM structure of human NatB complex
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