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6wpq
From Proteopedia
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==GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant== | ==GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant== | ||
| - | <StructureSection load='6wpq' size='340' side='right'caption='[[6wpq]]' scene=''> | + | <StructureSection load='6wpq' size='340' side='right'caption='[[6wpq]], [[Resolution|resolution]] 1.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WPQ OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6wpq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WPQ FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wpq OCA], [https://pdbe.org/6wpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wpq RCSB], [https://www.ebi.ac.uk/pdbsum/6wpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wpq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Boyer DR]] | [[Category: Boyer DR]] | ||
Current revision
GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant
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Categories: Homo sapiens | Large Structures | Boyer DR | Cao Q | Cascio D | Eisenberg DS | Hughes MP | Lu J | Sawaya MR
