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6x4s
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==MCU-EMRE complex of a metazoan mitochondrial calcium uniporter== | ==MCU-EMRE complex of a metazoan mitochondrial calcium uniporter== | ||
| - | <StructureSection load='6x4s' size='340' side='right'caption='[[6x4s]]' scene=''> | + | <StructureSection load='6x4s' size='340' side='right'caption='[[6x4s]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X4S OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6x4s]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tribolium_castaneum Tribolium castaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6X4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6X4S FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6x4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6x4s OCA], [https://pdbe.org/6x4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6x4s RCSB], [https://www.ebi.ac.uk/pdbsum/6x4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6x4s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D6X268_TRICA D6X268_TRICA] Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.[RuleBase:RU369077][https://www.uniprot.org/uniprot/D6WIX5_TRICA D6WIX5_TRICA] Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[RuleBase:RU367035] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Mitochondrial calcium uniporter|Mitochondrial calcium uniporter]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Tribolium castaneum]] | ||
[[Category: Baradaran R]] | [[Category: Baradaran R]] | ||
[[Category: Long SB]] | [[Category: Long SB]] | ||
[[Category: Wang C]] | [[Category: Wang C]] | ||
Current revision
MCU-EMRE complex of a metazoan mitochondrial calcium uniporter
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