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7jzh
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The Cryo-EM structure of the Glutamate decarboxylase from Escherichia coli== |
| - | + | <StructureSection load='7jzh' size='340' side='right'caption='[[7jzh]], [[Resolution|resolution]] 3.59Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7jzh]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7JZH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7JZH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.59Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7jzh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7jzh OCA], [https://pdbe.org/7jzh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7jzh RCSB], [https://www.ebi.ac.uk/pdbsum/7jzh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7jzh ProSAT]</span></td></tr> |
| - | [[Category: Su | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A5YKJ2_ECOLX A5YKJ2_ECOLX] Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.[ARBA:ARBA00024984] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Su C-C]] | ||
Current revision
The Cryo-EM structure of the Glutamate decarboxylase from Escherichia coli
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