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7k7v
From Proteopedia
(Difference between revisions)
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==The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: iodide derivative== | ==The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: iodide derivative== | ||
| - | <StructureSection load='7k7v' size='340' side='right'caption='[[7k7v]]' scene=''> | + | <StructureSection load='7k7v' size='340' side='right'caption='[[7k7v]], [[Resolution|resolution]] 1.88Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K7V OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[7k7v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7K7V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7K7V FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.882Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7k7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7k7v OCA], [https://pdbe.org/7k7v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7k7v RCSB], [https://www.ebi.ac.uk/pdbsum/7k7v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7k7v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SSR4_SCHPO SSR4_SCHPO] Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.<ref>PMID:18622392</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Newman J]] | [[Category: Newman J]] | ||
[[Category: Peat TS]] | [[Category: Peat TS]] | ||
Current revision
The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: iodide derivative
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