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7kpw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the H-lobe of yeast CKM== | |
| + | <StructureSection load='7kpw' size='340' side='right'caption='[[7kpw]], [[Resolution|resolution]] 4.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7kpw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KPW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kpw OCA], [https://pdbe.org/7kpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kpw RCSB], [https://www.ebi.ac.uk/pdbsum/7kpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kpw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SRB8_YEAST SRB8_YEAST] Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.<ref>PMID:12200444</ref> <ref>PMID:15601835</ref> <ref>PMID:16076843</ref> <ref>PMID:16109375</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Mediator|Mediator]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Boyer TG]] | ||
| + | [[Category: Chang CE]] | ||
| + | [[Category: Chao TC]] | ||
| + | [[Category: Chen SF]] | ||
| + | [[Category: Cholko T]] | ||
| + | [[Category: Garcia BA]] | ||
| + | [[Category: Kim HJ]] | ||
| + | [[Category: Li YC]] | ||
| + | [[Category: Murakami K]] | ||
| + | [[Category: Nakanishi K]] | ||
| + | [[Category: Tsai KL]] | ||
Current revision
Structure of the H-lobe of yeast CKM
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Categories: Large Structures | Saccharomyces cerevisiae S288C | Boyer TG | Chang CE | Chao TC | Chen SF | Cholko T | Garcia BA | Kim HJ | Li YC | Murakami K | Nakanishi K | Tsai KL
