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7lup
From Proteopedia
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| - | ==== | + | ==Human TRiC/CCT complex with reovirus outer capsid protein sigma-3== |
| - | <StructureSection load='7lup' size='340' side='right'caption='[[7lup]]' scene=''> | + | <StructureSection load='7lup' size='340' side='right'caption='[[7lup]], [[Resolution|resolution]] 6.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7lup]] is a 17 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mammalian_orthoreovirus_3_Dearing Mammalian orthoreovirus 3 Dearing]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7LUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7LUP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lup OCA], [https://pdbe.org/7lup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lup RCSB], [https://www.ebi.ac.uk/pdbsum/7lup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lup ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7lup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7lup OCA], [https://pdbe.org/7lup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7lup RCSB], [https://www.ebi.ac.uk/pdbsum/7lup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7lup ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Hereditary sensory and autonomic neuropathy with spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TCPE_HUMAN TCPE_HUMAN] Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.<ref>PMID:20080638</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Chaperonin 3D structures|Chaperonin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mammalian orthoreovirus 3 Dearing]] |
| + | [[Category: Aebersold R]] | ||
| + | [[Category: Chiu W]] | ||
| + | [[Category: Dermody TS]] | ||
| + | [[Category: Frydman J]] | ||
| + | [[Category: Gestaut D]] | ||
| + | [[Category: Knowlton JJ]] | ||
| + | [[Category: Leitner A]] | ||
| + | [[Category: Ma B]] | ||
| + | [[Category: Prasad BVV]] | ||
| + | [[Category: Seven AB]] | ||
| + | [[Category: Shanker S]] | ||
| + | [[Category: Taylor G]] | ||
| + | [[Category: Wilson GJ]] | ||
| + | [[Category: Yates NA]] | ||
Current revision
Human TRiC/CCT complex with reovirus outer capsid protein sigma-3
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Categories: Homo sapiens | Large Structures | Mammalian orthoreovirus 3 Dearing | Aebersold R | Chiu W | Dermody TS | Frydman J | Gestaut D | Knowlton JJ | Leitner A | Ma B | Prasad BVV | Seven AB | Shanker S | Taylor G | Wilson GJ | Yates NA
