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5t3a
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5t3a is ON HOLD until Paper Publication Authors: Cook, N.J., Pye, V.E., Cherepanov, P. Description: Visna virus integrase CCD-CTD (residues 60-275)...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Maedi-Visna virus (MVV) integrase CCD-CTD (residues 60-275)== | |
| + | <StructureSection load='5t3a' size='340' side='right'caption='[[5t3a]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5t3a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Visna-maedi_virus Visna-maedi virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T3A FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.501Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3a OCA], [https://pdbe.org/5t3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t3a RCSB], [https://www.ebi.ac.uk/pdbsum/5t3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/POL_VILVK POL_VILVK] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. | ||
| - | + | ==See Also== | |
| - | + | *[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Cherepanov | + | [[Category: Visna-maedi virus]] |
| - | [[Category: Cook | + | [[Category: Cherepanov P]] |
| + | [[Category: Cook NJ]] | ||
| + | [[Category: Pye VE]] | ||
Current revision
Maedi-Visna virus (MVV) integrase CCD-CTD (residues 60-275)
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