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5tcd
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine== | |
| + | <StructureSection load='5tcd' size='340' side='right'caption='[[5tcd]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5tcd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCD FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tcd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tcd OCA], [https://pdbe.org/5tcd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tcd RCSB], [https://www.ebi.ac.uk/pdbsum/5tcd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tcd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ENPP7_HUMAN ENPP7_HUMAN] Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.<ref>PMID:12885774</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ectonucleotide pyrophosphatase/phosphodiesterase 3D structures|Ectonucleotide pyrophosphatase/phosphodiesterase 3D structures]] | |
| - | + | *[[Sphingomyelinase|Sphingomyelinase]] | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Gorelik A]] | ||
| + | [[Category: Illes K]] | ||
| + | [[Category: Liu F]] | ||
| + | [[Category: Nagar B]] | ||
Current revision
Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine
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Categories: Homo sapiens | Large Structures | Gorelik A | Illes K | Liu F | Nagar B
