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5tcr

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{{Large structure}}
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==Atomic model of the Salmonella SPI-1 type III secretion injectisome basal body proteins InvG, PrgH, and PrgK==
==Atomic model of the Salmonella SPI-1 type III secretion injectisome basal body proteins InvG, PrgH, and PrgK==
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<StructureSection load='5tcr' size='340' side='right' caption='[[5tcr]], [[Resolution|resolution]] 6.30&Aring;' scene=''>
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<SX load='5tcr' size='340' side='right' viewer='molstar' caption='[[5tcr]], [[Resolution|resolution]] 6.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tcr]] is a 63 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TCR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tcr]] is a 63 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TCR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TCR FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tcp|5tcp]], [[5tcq|5tcq]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tcr OCA], [http://pdbe.org/5tcr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tcr RCSB], [http://www.ebi.ac.uk/pdbsum/5tcr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tcr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tcr OCA], [https://pdbe.org/5tcr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tcr RCSB], [https://www.ebi.ac.uk/pdbsum/5tcr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tcr ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
 
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/INVG_SALTY INVG_SALTY]] Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants. [[http://www.uniprot.org/uniprot/PRGH_SALTY PRGH_SALTY]] Required for invasion of epithelial cells. [[http://www.uniprot.org/uniprot/PRGK_SALTY PRGK_SALTY]] Required for invasion of epithelial cells. Could be involved in protein secretion.
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[https://www.uniprot.org/uniprot/SCTC1_SALTY SCTC1_SALTY] Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:9786184, PubMed:27974800, PubMed:30242280). Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane (PubMed:9786184, PubMed:21385715, PubMed:27974800, PubMed:30242280).<ref>PMID:21385715</ref> <ref>PMID:27974800</ref> <ref>PMID:30242280</ref> <ref>PMID:9786184</ref>
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== References ==
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<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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[[Category: Large Structures]]
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[[Category: Bergeron, J R.C]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Hong, C]]
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[[Category: Bergeron JRC]]
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[[Category: Huang, R K]]
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[[Category: Hong C]]
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[[Category: Strynadka, N C.J]]
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[[Category: Huang RK]]
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[[Category: Vuckovic, M]]
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[[Category: Strynadka NCJ]]
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[[Category: Worrall, L J]]
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[[Category: Vuckovic M]]
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[[Category: Yu, Z]]
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[[Category: Worrall LJ]]
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[[Category: Bacterial]]
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[[Category: Yu Z]]
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[[Category: Injectisome]]
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[[Category: Membrane protein]]
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[[Category: Secretion]]
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Current revision

Atomic model of the Salmonella SPI-1 type III secretion injectisome basal body proteins InvG, PrgH, and PrgK

5tcr, resolution 6.30Å

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