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5tja
From Proteopedia
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==I-II linker of TRPML1 channel at pH 6== | ==I-II linker of TRPML1 channel at pH 6== | ||
| - | <StructureSection load='5tja' size='340' side='right' caption='[[5tja]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5tja' size='340' side='right'caption='[[5tja]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5tja]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJA OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5tja]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TJA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tja OCA], [https://pdbe.org/5tja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tja RCSB], [https://www.ebi.ac.uk/pdbsum/5tja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tja ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN] Mucolipidosis type 4. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN] Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.<ref>PMID:12459486</ref> <ref>PMID:14749347</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Benvin | + | [[Category: Homo sapiens]] |
| - | [[Category: Li | + | [[Category: Large Structures]] |
| - | [[Category: Li | + | [[Category: Benvin NM]] |
| - | [[Category: Li | + | [[Category: Li H]] |
| - | [[Category: Michailidis | + | [[Category: Li M]] |
| - | [[Category: Su | + | [[Category: Li X]] |
| - | [[Category: Tong | + | [[Category: Michailidis IE]] |
| - | [[Category: Wang | + | [[Category: Su D]] |
| - | [[Category: Yang | + | [[Category: Tong L]] |
| - | [[Category: Zhang | + | [[Category: Wang S]] |
| - | [[Category: Zhou | + | [[Category: Yang J]] |
| - | + | [[Category: Zhang WK]] | |
| - | + | [[Category: Zhou X]] | |
| - | + | ||
| - | + | ||
Current revision
I-II linker of TRPML1 channel at pH 6
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Categories: Homo sapiens | Large Structures | Benvin NM | Li H | Li M | Li X | Michailidis IE | Su D | Tong L | Wang S | Yang J | Zhang WK | Zhou X
