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5u0s
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5u0s is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the Mediator-RNAPII complex== | |
| + | <SX load='5u0s' size='340' side='right' viewer='molstar' caption='[[5u0s]], [[Resolution|resolution]] 7.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5u0s]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U0S FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.8Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0s OCA], [https://pdbe.org/5u0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u0s RCSB], [https://www.ebi.ac.uk/pdbsum/5u0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MED6_SCHPO MED6_SCHPO] Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | ||
| - | + | ==See Also== | |
| - | + | *[[Mediator|Mediator]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe]] | ||
| + | [[Category: Asturias F]] | ||
| + | [[Category: Chao T-C]] | ||
| + | [[Category: Conaway JW]] | ||
| + | [[Category: Conaway RC]] | ||
| + | [[Category: Florens L]] | ||
| + | [[Category: Gopalan S]] | ||
| + | [[Category: Murakami K]] | ||
| + | [[Category: Tsai K-L]] | ||
| + | [[Category: Washburn MP]] | ||
| + | [[Category: Yu X]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Cryo-EM structure of the Mediator-RNAPII complex
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Categories: Large Structures | Schizosaccharomyces pombe | Asturias F | Chao T-C | Conaway JW | Conaway RC | Florens L | Gopalan S | Murakami K | Tsai K-L | Washburn MP | Yu X | Zhang Y
