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8pui
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8pui is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==human PHOX2B C-terminal domain including the polyA fragment at 298K== | |
| - | + | <StructureSection load='8pui' size='340' side='right'caption='[[8pui]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8pui]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PUI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pui OCA], [https://pdbe.org/8pui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pui RCSB], [https://www.ebi.ac.uk/pdbsum/8pui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pui ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/PHX2B_HUMAN PHX2B_HUMAN] Neuroblastoma;Congenital central hypoventilation syndrome;Hirschsprung disease-ganglioneuroblastoma syndrome;Haddad syndrome. The disease is caused by variants affecting the gene represented in this entry. Disease susceptibility is associated with variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHX2B_HUMAN PHX2B_HUMAN] Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Anton R]] | ||
| + | [[Category: Babu M]] | ||
| + | [[Category: Cabrita EJ]] | ||
| + | [[Category: Felix S]] | ||
| + | [[Category: Oroz J]] | ||
| + | [[Category: Pantoja-Uceda D]] | ||
| + | [[Category: Tinnefeld P]] | ||
| + | [[Category: Trevino MA]] | ||
| + | [[Category: Vera AM]] | ||
| + | [[Category: Zweckstetter M]] | ||
Current revision
human PHOX2B C-terminal domain including the polyA fragment at 298K
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Categories: Homo sapiens | Large Structures | Anton R | Babu M | Cabrita EJ | Felix S | Oroz J | Pantoja-Uceda D | Tinnefeld P | Trevino MA | Vera AM | Zweckstetter M
